This research note analyzes the relationship between indicators of corporate social and financial performance within a comprehensive theoretical framework. The results, based on data for 67 large U.S. corporations for 1982-1992, reveal no significant negative social-financial performance relationships and strong positive correlations in both contemporaneous and lead-lag formulations.

Magnetic resonance imaging (MRI) can provide a number of measurements relevant to sport-related concussion (SRC) symptoms; however, most studies to date have used a single MRI modality and whole-brain exploratory analyses in attempts to localize concussion injury. This has resulted in highly variable findings across studies due to wide ranging symptomology, severity and nature of injury within studies. A multimodal MRI, symptom-guided region-of-interest (ROI) approach is likely to yield more consistent results. The functions of the cerebellum and basal ganglia transcend (...) many common concussion symptoms, and thus these regions, plus the white matter tracts that connect or project from them, constitute plausible ROIs for MRI analysis. We performed diffusion tensor imaging (DTI), resting-state functional MRI, quantitative susceptibility mapping (QSM), and cerebral blood flow (CBF) imaging using arterial spin labeling (ASL), in youth aged 12-18 years following SRC, with a focus on the cerebellum, basal ganglia and white matter tracts. Compared to controls similar in age, sex and sport (N = 20), recent SRC youth (N = 29; MRI at 8 ± 3 days post injury) exhibited increased susceptibility in the cerebellum (p = 0.032), decreased functional connectivity between the caudate and each of the pallidum (p = 0.035) and thalamus (p = 0.021), and decreased diffusivity in the mid-posterior corpus callosum (p < 0.038); no changes were observed in recovered asymptomatic youth (N = 16; 41 ± 16 days post injury). For recent symptomatic-only SRC youth (N = 24), symptom severity was associated with increased susceptibility in the superior cerebellar peduncles (p = 0.011) and reduced activity in the cerebellum (p = 0.013). Fewer days between injury and MRI were associated with reduced cerebellar-parietal functional connectivity (p < 0.014), reduced activity of the pallidum (p = 0.002), increased CBF in the caudate (p = 0.005), and reduced diffusivity in the central corpus callosum (p < 0.05). Youth SRC is associated with acute cerebellar inflammation accompanied by reduced cerebellar activity and cerebellar-parietal connectivity, as well as structural changes of the middle regions of the corpus callosum accompanied by functional changes of the caudate, all of which resolve with recovery. Early MRI post-injury is important to establish objective MRI-based indicators for concussion diagnosis, recovery assessment and prediction of outcome. (shrink)

This paper reviews the fate of the central ideas behind the complementary learning systems (CLS) framework as originally articulated in McClelland, McNaughton, and O’Reilly (1995). This framework explains why the brain requires two differentially specialized learning and memory systems, and it nicely specifies their central properties (i.e., the hippocampus as a sparse, pattern-separated system for rapidly learning episodic memories, and the neocortex as a distributed, overlapping system for gradually integrating across episodes to extract latent semantic structure). We review the application (...) of the CLS framework to a range of important topics, including the following: the basic neural processes of hippocampal memory encoding and recall, conjunctive encoding, human recognition memory, consolidation of initial hippocampal learning in cortex, dynamic modulation of encoding versus recall, and the synergistic interactions between hippocampus and neocortex. Overall, the CLS framework remains a vital theoretical force in the field, with the empirical data over the past 15 years generally confirming its key principles. (shrink)

This book treats practical and political reasoning as an active engagement with the world and other people; it cannot be understood as exclusively cognitive and this is seen as a virtue rather than a deficiency. Informal, emotional, characterological, aesthetic and interactional aspects of thought can be constituents of reasonable arguing. The work examines key capacities connected with argumentation, in a variety of fields from professional and medical ethics to work organization and the practice of art.

We attempt to defend the species-as-individuals hypothesis by examining the logical role played by the binomials (e.g., "Homo sapiens," "Pinus ponderosa") in biological discourse about species. Those who contend that the binomials can be properly understood as functioning in biological theory as singular terms opt for an objectual account of species and view species as individuals. Those who contend that the binomials can in principle be eliminated from biological theory in favor of predicate expressions opt for a predicative account of (...) species and view species as kinds. We contend that biologists' talk about species is talk about species as individuals, and we conclude that the most plausible account of species is an objectual account. (shrink)

Qualitative research is a key form of research in education; the findings of such projects frequently play a central role in shaping policy and practice. First time qualitative researchers require clear and practical guidance from the outset. However, given the diversity of both subject matter and methodological approaches encompassed by qualitative research, such guidance is not always easily come by. _Qualitative Educational Research in Action: Doing and Reflecting_ is a collection of ten first-hand accounts by educational researchers of qualitative inquiries (...) they carried out. The subjects are diverse, taking in school restructuring, policy analysis, critical literacy, phenomenology and the student teacher relationship. Each chapter outlines the research question investigated and provides an overview of the project's findings, before going on to describe how each researcher approached the challenges of their particular inquiry. The researchers reflect upon the unexpected turns qualitative research can take and the way such projects can move through different theoretical and methodological positions, often ending up significantly removed from the original premise, but all the more valuable for that. Anyone conducting qualitative research in education will be heartened and inspired by this collection, and will also find in it invaluable guidance on dealing effectively with the idiosyncrasies and pitfalls of qualitative research - guidance that is all the more valuable for coming from those who have themselves navigated similar difficulties. (shrink)

The prefrontal cortex is widely believed to play an important role in facilitating people's ability to switch performance between different tasks. We present a biologically‐based computational model of prefrontal cortex (PFC) that explains its role in task switching in terms of the greater flexibility conferred by activation‐based working memory representations in PFC, as compared with more slowly adapting weight‐based memory mechanisms. Specifically we show that PFC representations can be rapidly updated when a task switches via a dynamic gating mechanism based (...) on a temporal‐differences reward‐prediction learning mechanism. Unlike prior models of this type, the present model develops all of its internal representations via learning mechanisms as shaped by the demands of continuous periodic task switching. This advance opens up a new domain of research into the interactions between working memory task demands and the representations that develop to meet them. Results on a version of the Wisconsin card sorting task are presented for the full model and a number of comparison networks that test the importance of various model features. Furthermore, we show that a lesioned model produces perseverative errors like those seen in frontal patients. (shrink)

The prefrontal cortex is widely believed to play an important role in facilitating people's ability to switch performance between different tasks. We present a biologically‐based computational model of prefrontal cortex (PFC) that explains its role in task switching in terms of the greater flexibility conferred by activation‐based working memory representations in PFC, as compared with more slowly adapting weight‐based memory mechanisms. Specifically we show that PFC representations can be rapidly updated when a task switches via a dynamic gating mechanism based (...) on a temporal‐differences reward‐prediction learning mechanism. Unlike prior models of this type, the present model develops all of its internal representations via learning mechanisms as shaped by the demands of continuous periodic task switching. This advance opens up a new domain of research into the interactions between working memory task demands and the representations that develop to meet them. Results on a version of the Wisconsin card sorting task are presented for the full model and a number of comparison networks that test the importance of various model features. Furthermore, we show that a lesioned model produces perseverative errors like those seen in frontal patients. (shrink)

The collection presents a variety of promising new directions in Royce scholarship from an international group of scholars, including historical reinterpretations, explorations of Royce's ethics of loyalty and religious philosophy, and contemporary applications of his ideas in psychology, the problem of reference, neo-pragmatism, and literary aesthetics.

Compared to our understanding of positive prediction error signals occurring due to unexpected reward outcomes, less is known about the neural circuitry in humans that drives negative prediction errors during omission of expected rewards. While classical learning theories such as Rescorla–Wagner or temporal difference learning suggest that both types of prediction errors result from a simple subtraction, there has been recent evidence suggesting that different brain regions provide input to dopamine neurons which contributes to specific components of this prediction error (...) computation. Here, we focus on the brain regions responding to negative prediction error signals, which has been well-established in animal studies to involve a distinct pathway through the lateral habenula. We examine the activity of this pathway in humans, using a conditioned inhibition paradigm with high-resolution functional MRI. First, participants learned to associate a sensory stimulus with reward delivery. Then, reward delivery was omitted whenever this stimulus was presented simultaneously with a different sensory stimulus, the conditioned inhibitor. Both reward presentation and the reward-predictive cue activated midbrain dopamine regions, insula and orbitofrontal cortex. While we found significant activity at an uncorrected threshold for the CI in the habenula, consistent with our predictions, it did not survive correction for multiple comparisons and awaits further replication. Additionally, the pallidum and putamen regions of the basal ganglia showed modulations of activity for the inhibitor that did not survive the corrected threshold. (shrink)

The posterior cortex, hippocampus, and prefrontal cortex in the Leabra architecture are specialized in terms of various neural parameters, and thus are predilections for learning and processing, but domain-general in terms of cognitive functions such as face recognition. Also, these areas are not encapsulated and violate Fodorian criteria for modularity. Anderson's terminology obscures these important points, but we applaud his overall message.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

ABSTRACT There is limited guidance about whether and how to provide psychological assessment results to research participants. This paper considers several ethical challenges associated with offering individual research results in psychological assessment research. Additionally, the process used to return individual results within a study examining neurodevelopmental effects of anesthesia exposure in children and adolescents is described. Almost all participants requested to know if results were concerning; however, only around a third of those with concerning findings sought additional feedback. Ongoing research (...) and guidance are necessary to establish evidence-based practices and manage challenges that may emerge when disclosing such results. (shrink)

BackgroundDespite rapid growth of the scientific literature, no consensus guidelines have emerged to define the optimal criteria for editors to grade submitted manuscripts. The purpose of this project was to assess the peer reviewer metrics currently used in the surgical literature to evaluate original manuscript submissions.MethodsManuscript grading forms for 14 of the highest circulation general surgery-related journals were evaluated for content, including the type and number of quantitative and qualitative questions asked of peer reviewers. Reviewer grading forms for the seven (...) surgical journals with the higher impact factors were compared to the seven surgical journals with lower impact factors using Fisher’s exact tests.ResultsImpact factors of the studied journals ranged from 1.73 to 8.57, with a median impact factor of 4.26 in the higher group and 2.81 in the lower group. The content of the grading forms was found to vary considerably. Relatively few journals asked reviewers to grade specific components of a manuscript. Higher impact factor journal manuscript grading forms more frequently addressed statistical analysis, ethical considerations, and conflict of interest. In contrast, lower impact factor journals more commonly requested reviewers to make qualitative assessments of novelty/originality, scientific validity, and scientific importance.ConclusionSubstantial variation exists in the grading criteria used to evaluate original manuscripts submitted to the surgical literature for peer review, with differential emphasis placed on certain criteria correlated to journal impact factors. (shrink)

En esta investigación se presenta el estudio de cinco perspectivas de análisis de la obra filosófica de Ignacio Ellacuría, con la finalidad de ofrecer un panorama general, que permita profundizar en su pensamiento. Se parte de la perspectiva ofrecida por Antonio González, como uno de los primeros sistematizadores del corpus ellacuriano, para dar paso a la interpretación elaborada por Héctor Samour, caracterizada por su visión de continuidad en cada una de las etapas filosóficas de Ellacuría. Luego, se ahonda en la (...) lectura metafísica propuesta por Marcela Brito; para posteriormente estudiar la perspectiva hecha por José M. Romero-Cuevas, la cual se encuentra en relación directa con la teoría crítica y las ideas de Juan A. Nicolás, en cuyo enfoque sobresale el papel de la verdad y la experiencia en la filosofía madura de Ellacuría. Para finalizar, se presentan las propuestas que analizan a este autor desde la óptica de los derechos humanos, tomando en cuenta los aportes de Juan A. Senent y Alejandro Rosillo. (shrink)

To explore the realm of creativity, we will make use of the concept of instauration as articulated in the work of Étienne Souriau. Although infrequently used, the word remains extant in English, with agreement among dictionaries that the primary definition is the action of restoring or renewing, with a secondary meaning of instituting or founding. While both senses are at play in Souriau’s thought, it is perhaps the tension between the two that is predominantly in question, akin to what we (...) describe as open containment. We think instauration, as institutive renewal, in dialogue with Merleau-Ponty’s late use of the term aesthesiology to further elaborate the process of creating as a return to the wonder that is aesthesis, the affectively and sensually apprehended opening onto and entanglement with what is. Merleau-Ponty extends aesthesiology as the science of the sense organs themselves into a philosophical organology for ontology. His use of aesthesiology and Souriau’s use of instauration constitute efforts to offer sufficient conceptual containment to be able to say the contingent and ambiguous open of ongoing originating, even while both thinkers strive not to institute any final closure by this very act of naming. This is the inevitable tension of writing philosophic creation.Pour explorer le royaume de la créativité, nous utilisons ici le concept d’instauration tel qu’il a été articulé dans l’oeuvre d’Étienne Souriau. Quoique utilisé rarement, ce terme est attesté dans la langue anglaise. Les dictionnaires anglais accordent que sa définition principale désigne une action de rétablissement ou de renouvellement, avec un sens secondaire d’institution ou fondation. Si les deux sens sont à l’oeuvre chez Souriau, c’est peut-être la tension entre eux qui y est surtout patente. Nous pensons ici l’instauration, entendue comme renouvellement instituant, en dialogue avec l’idée d’esthésiologie telle que Merleau-Ponty la comprend à la fin de son oeuvre. Il utilise cette notion pour développer sa conception du processus de création comme retour à l’étonnement que produit l’áisthesis. L’áisthesis est en effet l’ouverture, affective et sensible, et l’entrelacs, affectif et sensible, à ce qui est. Merleau-Ponty prolonge ainsi l’esthésiologie entendue comme science des organes sensibles, vers une organologie philosophique à visée ontologique. L’usage de l’esthésiologie chez Merleau-Ponty et l’usage de l’instauration chez Souriau constituent des efforts vers une maîtrise conceptuelle suffisante pour pouvoir dire l’ouverture continue, contingente et ambiguë de l’originaire – bien que les deux penseurs ne visent pas à instaurer une clôture finale à partir de l’acte nominatif. Telle est la tension inévitable qu’on rencontre lorsqu’on cherche à écrire la création philosophique.Utilizzeremo in queste pagine per esplorare il regno della creatività il concetto di “instaurazione” così come si trova articolato nell’opera di Étienne Souriau. Benché impiegato raramente, questo termine è attestato anche nella lingua inglese. I dizionari inglesi danno come significato principale quello di un’azione di ristabilimento o rinnovamento, a cui si aggiunge un significato secondario di istituzione o fondazione. Se è vero che entrambi i significati sono all’opera in Souriau, è d’altra parte ancor più evidente la loro tensione. Proporremo qui di pensare l’instaurazione, intesa come rinnovamento istituente, in dialogo con l’idea di estesiologia così come la intende Merleau-Ponty alla fine del suo percorso. Egli usa questa nozione per sviluppare la sua concezione del processo creativo come ritorno allo stupore dell’áisthesis, cioè dell’apertura affettiva e sensibile, e dell’intreccio affettivo e sensibile, a ciò che è. Merleau-Ponty prolunga così l’estesiologia come scienza degli organi di senso in direzione di un’organologia filosofica orientata ontologicamente. L’indagine sull’estesiologia condotta da Merleau-Ponty e l’uso del concetto di instaurazione in Souriau costituiscono così altrettanti sforzi di dire concettualmente l’apertura continua, contingente e ambigua dell’originario – benché sia chiaro che i due pensatori non intendono raggiungere in alcun modo, con questo dire concettuale e con questa scelta lessicale, una qualsiasi “chiusura” della questione. Tale è infatti la tensione inevitabile cui ci si ritrova esposti quando si tenta di scrivere la creazione. (shrink)